Searchable abstracts of presentations at key conferences in endocrinology

ea0012p112 | Reproduction | SFE2006

Functional pharmacology of prostaglandin EP agonists in isolated human myometrium from term pregnant donors

Fischer DP , Farrar D , O’Donovan P , Senior J , Woodward DF , Marshall KM

Prostaglandin (PG) E2 acts through its receptors (EP1–4) to influence uterine contractility during gestation and parturition. The aim of the present study was to identify functional EP receptor targets in isolated myometrium from term pregnant, non-labouring donors by use of specific and novel EP agonists.Biopsies of human myometrium were obtained at elective caesarean section from consenting term pregnant women, not in labour ...